Recent Advances in Research on <I>Malassezia</I> Microbiota in Humans

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  • Sugita Takashi
    Department of Microbiology, Meiji Pharmaceutical University
  • Zhang Enshi
    Department of Microbiology, Meiji Pharmaceutical University Department of Dermatology, Tokyo Medical University
  • Tanaka Takafumi
    Department of Microbiology, Meiji Pharmaceutical University
  • Nishikawa Akemi
    Department of Immunobiology, Meiji Pharmaceutical University
  • Tajima Mami
    Department of Dermatology, Tokyo Medical University
  • Tsuboi Ryoji
    Department of Dermatology, Tokyo Medical University

Bibliographic Information

Other Title
  • ヒト皮膚常在真菌 <I>Malassezia</I> の菌叢解析に関する up to date
  • ヒト皮膚常在真菌Malasseziaの菌叢解析に関するup to date
  • ヒト ヒフ ジョウザイ シンキン Malassezia ノ キンソウカイセキ ニ カンスル up to date
  • Recent Advances in Research on Malassezia Microbiota in Humans

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Description

Malassezia species of lipophilic yeasts account for most fungal microbiota. Although they colonize healthy skin, they are also associated with several skin diseases, including pityriasis versicolor, seborrheic dermatitis, Malassezia folliculitis, and atopic dermatitis. To date, 14 members of the Malassezia genus have been identified. Of these, both M. globosa and M. restricta predominate, regardless of skin-disease type. Comprehensive analysis of fungal microbiota in the skin of patients with atopic dermatitis using an rRNA clone library method revealed that fungal microbiota cluster according to disease severity. The external ear canal and sole of the foot are colonized by specific Malassezia microbiota.

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