Pathological Chahge of the Lung Caused by Air-pollution, Especially on the Pulmonary Cancer

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  • TAKEMOTO Kazuo
    Saitama Medical College, Public Health Tokyo Medical & Dental University, Scool of Medicine, Public Health

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  • 大気汚染による肺の病変, 特に肺がんについて

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Main factors contributing to the etiology of the lung cancer have been assumed to be cigarettes-smoking, air-pollution, occupational exposure, etc. The author made studies on the interrelationship between the air-pollution and the lung cancer. It was impossible to separate the air-pollution factor, the human lung cancer was caused by superposition of the several factors.<BR>Pathological and histhological studies usings of dogs revealed that the frequency of highly contaminated lungs (anthracosis) was 44o out of 835 cases (53%) in Tokyo, while that of less-polluted area was 226 out of 902 cases (25%). similar results were obtained in case of lungs of pigeons. The lung cancer of the examined dog was found in 6 cases in Tokyo, and none in other areas. The experimental stimulation of the lung tumor was carried out by simultaneous application of carbon black and carcinogens with the result that carbon black accelerated the condition.

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