SOME LASER-TISSUE INTERACTIONS IN 308 NM EXCIMER LASER CORONARY ANGIOPLASTY
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- Gijsbers Geert H. M.
- Laser Center
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- Sprangers Rene L. H.
- Laser Center
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- Keijzer Marleen
- Department of Mathematics and Informatics, Delft University of Technology
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- Bakker Jacques M. T. de
- Department of Experimental Cardiology Academic Medical Center
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- Leeuwen Ton G. van
- Department of Cardiology, Heart Lung Institute University Hospital Utrecht
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- Verdaasdonk Rudolf M.
- Department of Cardiology, Heart Lung Institute University Hospital Utrecht
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- Borst Cornelius
- Department of Cardiology, Heart Lung Institute University Hospital Utrecht
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- Gemert Martin J. C. van
- Department of Cardiology, Heart Lung Institute University Hospital Utrecht
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説明
Some physical concepts of laser-tissue interactions that occur in 308nm excimer laser angioplasty are addressed. Monte Carlo numerical computations were used to analyze the light fluence rate distributions resulting from finite diameter laser beams incident on tissue, as applied by fiber optic light delivery catheters. The fluence rate at the inside part of the tissue surface from a 0.2mm diameter fiber emitting 308nm light, is increased more than twice relative to the incident power density. The light fluence rate distribution inside the tissue spreads very little outside the incident beam diameter. Therefore, the distributions from different fibers in multifiber catheters will not overlap unless the fibers are very close together. The maximum fluence rate decreases with decreasing beam diameters, Ablation of tissue by a 308nm excimer laser delivery system in contact with the tissue resulted in a damage zone adjacent to the crater wall due to expansion of the gaseous debris trapped under the tip of delivery system. In case of contact irradiation, the ablation was much more efficient than in case of non contact irradiation. Direct temperature measurements during excimer laser ablation by an IR camera showed that temperature accumulation will occur when a sequence of pulses is applied at frequencies of at least 5Hz. The temperature rise above ambient under circumstances simulating clinical conditions is measured to be 66±7°C.
収録刊行物
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- The Journal of Japan Society for Laser Surgery and Medicine
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The Journal of Japan Society for Laser Surgery and Medicine 11 (Supplement), 11-26, 1990
Japan Society for Laser Surgery and Medicine
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詳細情報 詳細情報について
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- CRID
- 1390001205454209920
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- NII論文ID
- 130004629920
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- ISSN
- 02886200
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可