Electroencephalographic study of the effects of benzene administration on neo-, paleo- and archicortical systems of rabbits

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  • Ageishi Hisao
    Department of Higiene and Public Healtq, Kansai Medical School

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Other Title
  • 二硫化炭素の家兎大脳新,旧,古皮質系の電気的活動に及ぼす影響に関する実験的研究

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The auther studied on the effects of benzene 0.15cc/kg on the EEG in cerebral neocortex, hippocampus and amygdala of intakt rabbits.<BR>The results obtained as followed.<BR>1) The arousal grade of EEG in neocortex, hippocampus and amygdala increases by administration of benzene. Spontaneous spindle burst in neocrtex disappeares completely.<BR>2) The sleep pattern on the neocortex followed administration of pentobarbi tal changes to the arousal pattern by aditional administration of benzene but the righting reflex does not recover.<BR>3) The thresholds of the arousal reaction on each activating systems for neo-, paleoand archi-cortex, including on the neocortical recuiting response, does not change after the administration of benzene.<BR>4) The increa sing of the arousal grade of EEG in neocortex, hippocampus and amygdala followed the administration of benzene may be due to the inhibitory of the medial reticular formation.

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