ウサギ赤血球溶血に及ぼすγ 線(<SUP>60</SUP>Co)照射の影響と糖質の抑制効果

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  • 笹 マツ子
    関西医科大学放射線科学教室 関西医科大学薬理学教室

書誌事項

タイトル別名
  • Protective Effect of Saccharides on Radiation-induced Hemolysis of Rabbit Erythrocytes
  • ウサギ赤血球溶血に及ぼすγ線(60Co)照射の影響と糖質の抑制効果
  • ウサギ セッケッキュウ ヨウケツ ニ オヨボス ガンマセン 60Co ショウシ

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抄録

The influence of radiation on the hemolysis of the extracted rabbit blood induced by cooling and the effects of glucose, sucrose, and galactose on the influence were examined.<BR>1) The degree of the hemolysis of the blood, which was stored in the cold r oom kept at a temperature of 7 °C, increased in proportion to the increase of the days during which the blood was stored, and the hemolysis was evident after 14 days.<BR>2) When the extracted blood had been irradiated by the cobalt radia tion at intensities more than 2,000 R, the hemolysis of the blood stored in the cold room was considerably accelerated.<BR>3) The cooling- and radiation-induced hemolysis was reduced by the addition of an isotonic glucose, sucrose, or galactose solution at concentrations higher than 12.5 volume percent of the irradiated blood.<BR>4) From the results, it was assumed that the membrane of rabbit erythrocyte might be influenced by the radiation at such low intensity as 2,000 R, and that the addition of isotonic glucose solution could protect the blood from the hemolysis induced by cooling and radiation.

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