Clinicopathological evaluation of prognostic factors on surgically resected cases of hilar cholangiocarcinoma

WATANABE Shigeru, BEPPU Tomoe, FUTAGAWA Syunji

doi:10.11210/tando1987.16.2_87

The results of surgical treatment for hilar cholangiocarcinoma were clinicopathologically evaluated to clarify prognostic factors. Among 42 patients with hilar cholangiocarcinoma treated in our department, curative resection was achieved only in 6 of 25 patients whom underwent surgery. These 25 surgically resected cases consisted of 9 cases of ss tumor,8 of se tumor, and 8 of si tumor. Although curative resection was achieved in 4 of the 9 patients with ss tumor, the other were all positive for resected stump including 2 patients with both positive stumps (hm & dm). Surgery for hilar cholangiocarcinoma resulted in non-curative resection in 14 of the 16 patients with se or si tumor. In 6 patients in whom curative resection was achieved,1-,3-, and 5-year survival rates were 83.3%,83.3%, and 55.6%, respectively. In the remaining 19 patients in whom curative resection was not achieved,1-,3-, and 5-year survival rates were 55.7%,5.6%, and 0%, respectively.<BR>Since all patients with hilar cholangiocarcinoma treated in our department, had advanced tumors at the time of diagnosis, many of them had positive bile stumps even after hepatectomy, resulting in non-curative resection. Thus, the outcome of non-curative resection cases was the same poor prognostis as that of non-operative cases.

Clinicopathological evaluation of prognostic factors on surgically resected cases of hilar cholangiocarcinoma

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