Five cases of herpetic gingivostomatitis and herpetic pharyngolaryngitis

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  • 単純ヘルペスウイルス性歯肉口内炎と咽喉頭炎の5例

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<p>Herpetic gingivostomatitis and pharyngolaryngitis are the most common clinical manifestations of primary herpes simplex virus (HSV) infection. Herpetic gingivostomatitis is characterized by the presence of multiple ulcer and stomatitis of the oral mucosa and frequently accompany swelling gingiva. Herpetic pharyngolaryngitis is characterized by the presence of multiple painful ulcer and stomatitis of the pharynx and larynx with the high fever and the poor state.</p><p>Detections of serum HSV antibodies are useful for the diagnosis of HSV infection. But it takes a week until serum anti HSV-IgM change to positive. So, for the accurate diagnosis of primary HSV infection, clinicians must wait for a week to check serum anti HSV-IgM. By taking care on this point, we diagnosed 5 pediatric patients as primary HSV infection.</p><p>Here we report 5 pediatric cases of HSV infection, 4 cases of gingivostomatitis and 1 case of pharyngolaryngitis. Nasopharyngolaryngo endoscope was useful in diagnosis of herpetic pharyngolaryngitis. The patients were 1 male and 4 females, aged from 2–17 years old. All patients had fever over 38 degrees centigrade, 4 patients complaint of sore throat and 3 patients had difficulty in oral intake. All patients were treated with acyclovir or valaciclovir and 1 patient with anti-biotics due to secondary bacterial infection. 2 patients were treated ambulatory and 3 patients were treated in the hospital. All patients recovered with no sequelae.</p>

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