Biogenesis of trans-acting siRNAs, endogenous secondary siRNAs in plants
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- Yoshikawa Manabu
- Division of Plant Sciences, National Institute of Agrobiological Sciences
書誌事項
- タイトル別名
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- Biogenesis of <i>trans</i>-acting siRNAs, endogenous secondary siRNAs in plants
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説明
Trans-acting small interfering RNAs (tasiRNAs) are plant-specific endogenous siRNAs that control non-identical mRNAs via cleavage. The production of tasiRNAs is triggered by cleavage of capped and polyadenylated primary TAS transcripts (pri-TASs) by specific miRNAs. Following miRNA-directed cleavage, either 5′ or 3′ cleavage fragments are converted into double-stranded RNAs (dsRNAs) by RNA-DEPENDENT RNA POLYMERASE 6. The dsRNAs are processed to tasiRNAs by DICER-LIKE 4 in a phasing manner. There are two forms of pri-TASs; One has a single miRNA target site that is targeted by 22-nucleotide microRNAs, and the other has two miR390 target sites. Secondary siRNAs that are important for the amplification of RNA silencing are defined as siRNAs whose production is initiated by the cleavage of primary small RNA-containing RNA-induced silencing complexes. Thus, tasiRNA production is a model system of secondary siRNA production in plants. This review focuses on the production of tasiRNAs that are endogenous secondary siRNAs.
収録刊行物
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- Genes & Genetic Systems
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Genes & Genetic Systems 88 (2), 77-84, 2013
日本遺伝学会
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詳細情報 詳細情報について
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- CRID
- 1390001205474257536
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- NII論文ID
- 10031183173
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- NII書誌ID
- AA11077421
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- COI
- 1:STN:280:DC%2BC3sjosl2gtA%3D%3D
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- ISSN
- 18805779
- 13417568
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- NDL書誌ID
- 024638433
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- PubMed
- 23832299
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可