グロンサン反応 (G反応) と他種肝機能検査法との比較研究

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  • COMPARATIVE STUDIES ON THE METHOD OF GURONSAN REACTION (G-REACTION) WITH OTHER KIND METHODS OF REACTION FOR LIVER FUNCTION TEST
  • グロンサン ハンノウ G ハンノウ ト タ シュ カン キノウ ケンサホウ ト ノ ヒカク ケンキュウ

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It is known that liver function has a many sided phase.<BR>Hence there are many means of liver function test. The author has compared the obtained results by the method of G-reaction, which was devised by K. Shozushima, with those of the other methods of reaction for liver function test as well as having traced the relation between G-reaction and serum protein picture.<BR>The results were revealed as follows: In the case of liver disease G-reaction revealed the higher positive degree than those of Thymol turbidity test (TTT), Serum iodic acid value, Takata's test, Gros' test, Sublimate test, Cobalt reaction, Zinc sulfate test, and Ehrlich's urobilinogen test, with the exception of Bromsulphalein test. In the case of hepatic infectiosa it revealed the positive rate of 90% and its responding degree recovered gradually in accordace with the cure of the symptoms. In the case of hepatic cirrhosis the positive rate was 100% and also in that of hepatic carcinoma it was 86.7%. In the case of nephropa thy the higher positive rate was seen in nephrosis and in chronic nephritis accompanied with nephrosis. Observing the corresponding rate between the results of G-reaction and those of the other kind methods, that is, 67.5% between it and Cobalt reaction, 65% between it and Sublimate test, 64.4% between it and Serum iodic acid value, 63.5% between it and T. T. T., 58.3% between it and Takata's test, 57.1% between it and Zinc sulfate test, and 54.5% between it and Gros' reaction.<BR>G-reaction had a correlationship respectively with those of Sublimate test, Serum iodic acid value, Gros' reaction, T. T. T., and icteric index. However, no correlation was recognized with those of Bromsulphalein test, Zinc sulfate test, Cobalt reaction, and Takata's test. From the observations of correlation between G-reaction and serum protein picture, though with no relation to serum total protein it had relation with Alumin and β + γ Globulin.<BR>From the present experimental studies, it is considered that the method of G-reaction for liver function test is so simple in its operation and so keen in its reaction that it is available to recommend as a means for clinical diagnosis.

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