CLINICAL EXPERIENCE WITH S-6436 IN ACUTE PYELONEPHRITIS

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  • S-6436の急性腎盂腎炎に対する使用経験
  • S-6436の急性腎盂炎に対する使用経験
  • S-6436 ノ キュウセイ ジンウエン ニ タイスル シヨウ ケイケン

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Abstract

S-6436 (a preparation consisting of 30% of non-enteric coated granules and 70% of enteric coated ones) was orally administered to the patients with acute pyelonephritis, and the following results were obtained:<BR>1. Subjective symptoms: Very good in 13 cases (65%), good in 1, fair in 2 and poor in 4.<BR>2. Urine finding: Very good in 13 cases (65%), good in 3 and poor in 4.<BR>3. Disappearance of causative organisms: Organisms which were identified in the first examination were 17 strains of E. coli, one each of Pr. vulgalis, Klebsiellaand Staph. epidermidis, 3 of Strept. faecalis, and 3 of mixed infections. Very good effect was observed in 16 cases, good in 1, fair in 1 and poor in 2.<BR>4. Total evaluation: Very good in 13 cases (65%), good in 4 (20%) and poor in 3 (15%).<BR>5. Slight discomfort in abdomen was observed in only one patient, but disappeared by administration of digestive.<BR>6. S-6436 was given to the patients with acute pyelonephritis twice a day expecting that the drug has satisfactory clinical efficacy.

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