BACTERIA ISOLATED FROM SURGICAL INFECTIONS AND ITS SUSCEPTIBILITIES TO ANTIMICROBIAL AGENTS

SHINAGAWA NAGAO, MIZUNO ISAMU, HIRATA KOICHI, KATSURAMAKI TADASHI, MIZUKUCHI TOHRU, USHIJIMA YASUHIDE, USHIDA TOMOHIRO, AIKAWA NAOKI, Yo KIKUO, TAKAYAMA TADATOSHI, ATO TAKESHIS, KATO KOUMEI, YURA JIRO, MANABE TADAO, TAKAYAMA HIROMITSU, WAKASUGI TAKEHIRO, TANIGUCHI MASAAKI, MASHITA KEIJI, ISHIKAWA SYU, MIZUNO AIURA, KUBO SHOJI, SUEHIRO SHIGEFUMI, FUJIMOTO MIKIO, HIGAKI KAZUYUKI, TANIMURA HIROSHI, TANIGUCHI KATSUTOSHI, TSUJI TAKESHI, OHNISHI HIRONOBU, YAMAUE HIROKI, KAWAI MANABU, TANAKA NORIAKI, IWAGAKI HIROMI, KIMURA HIDEYUKI, FUCHIMOTO SADAYOSHI, SUEDA TAIJIRO, HIYAMA EIZO, TAKESUE YOSHIO, MURAKAMI YOSHIAKI, OOGE HIROKI, UEMURA KENICHIRO, TSUMURA HIROAKI, YOKOYAMA TAKASHI, TAKEUCHI HITOSHI, YASUI YOSHIMASA, IKEDA SEIYO, YASUNAMI YOICHI, RYU SHINICHIRO

doi:10.11553/antibiotics1968b.60.59

Tendency of isolated bacteria from infections in abdominal surgery during theperiod from April 2005 to March 2006 were investigated in a multicenter study in Japan, and the following results were obtained.<BR>In this series, 384 strains including 18 strains of Candida spp. were isolated from 161 (70.3%) of 229 patients with surgical infections. One hundred and ninty-five strains were isolated from primary infections, and 171 strains were isolated from postoperative infections. From primary infections, aerobic Gram-negative bacteria and aerobic Gram-positive bacteria were predominant, while aerobic Gram-positive bacteria were predominant from postoperative infections. The isolation rate of aerobic Gram-positive bacteria, such as Enterococcus spp. and Staphylococcus aureus were higher from both types of infections. Among anaerobic Gram-positive bacteria, the isolation rate of Peptostreptococcus spp. was the highest from both types of infections. Among aerobic Gramnegative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Pseudomonas aeruginosa, Klebsiella spp. in this order, and from postoperative infections, E. coli was the most predominantly isolated, followed by Klebsiella pneumoniae and P. aeruginosa.<BR>Among anaerobic Gram-negative bacteria, the isolation rate of Bacteroides fragilis group was the highest from both primary and postoperative infections.<BR>In this series, we noticed no vancomycin-resistant Gram-positive cocci, nor multidrug-resistant P. aeruginosa. But cefazolin-resistant E. coil producing extended spectrum β-lactamase was seen in 5.0 per cents. We should be carefully followed up the facts that the increasing isolation rates of B. fragilis group and Bilophila wadsworthia which were resistant to both penicillins and cephems.

BACTERIA ISOLATED FROM SURGICAL INFECTIONS AND ITS SUSCEPTIBILITIES TO ANTIMICROBIAL AGENTS

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