Double Blind Controlled Trial of Pipemidic Acid in the Treatment on Chronic Suppurative Otitis Media
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- SAMBE Buemon
- Department of Otorhinolaryngology, Kanto Teishin Hospital
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- BABA Shunkichi
- Department of Otorhinolaryngology, Nagoya City University Medical School
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- IWASAWA Takehiko
- Clinic of Otorhinolaryngology, Sapporo Teishin Hospital
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- SUGIMORI Hisakazu
- Department of Otorhinolaryngology, Sapporo National Hospital
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- TOMURA Takuji
- Department of Otorhinolaryngology, Sapporo Railway Hospital
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- ABE Takao
- Department of Otorhinolaryngology, Sapporo City General Hospital
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- MIKATA Akiyoshi
- Department of Otorhinolaryngology, Hokkaido Central Hospital for Social Health Insurance
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- ITOH Tsutomu
- Department of Otorhinolaryngology, Ebetsu Municipal General Hospital
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- SASAKI Tooru
- Department of Otorhinolaryngology, Asahikawa Municipal Hospital
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- AWATAGUCHI Shogo
- Department of Otorhinolaryngology, Hirosaki University, Faculty of Medicine
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- EIRAOKA Mariko
- Department of Otorhinolaryngology, Hirosaki University, Faculty of Medicine
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- TAKAHASHI Kenichi
- Department of Otorhinolaryngology, Sendai National Hospital
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- INO Hatsuo
- Department of Otorhinolaryngology, Niigata University School of Medicine
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- MIYAO Masuyuki
- Department of Otorhinolaryngology, Niigata University School of Medicine
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- NAGABA Masao
- Department of Otorhinolaryngology, Niigata City Hospital
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- UMEDA Yoshio
- Department of Otorhinolaryngology, Tokyo Rosai Hospital
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- TAKAFUJI Tsuguo
- Department of Otorhinolaryngology, Tokyo Koseinenkin Hospital
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- OKUBO Yasushi
- Department of Otorhinolaryngology, Tokyo Medical and Dental Univerisity
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- HOSUI Masafumi
- Department of Otorhinolarynglogy, Tokyo Teishin Hospital
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- BONO Keiji
- Department of Otorhinolarynglogy, Tokyo Teishin Hospital
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- SATO Tsunemasa
- Department of Otorhinolaryngolgy, Tokyo Metropolitan Police Hospital
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- SHIMADA Kazuya
- Department of Otorhinolaryngology, Ichikawa Hospital, Tokyo Dental Collage
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- YANO Kensuke
- Department of Otorhinolaryngology, The Jikei University School of Medicine
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- UMESAWA Yuji
- Department of Otorhinolaryngology, The Jikei University School of Medicine
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- ZUSHO Hiroyuki
- Department of Otorhinolaryngology, Tokyo Seamen's Insurance Hospital
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- TORIYAMA Minoru
- Department of Otorhinolaryngology, Kanto Rosai Hospital
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- TAKEUCHI Minako
- Department of Otorhinolaryngology, Kanto Rosai Hospital
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- NANJYO Shoichi
- Department of Otorhinolaryngology, Kanto Chuo Hospital
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- INOUE Tetsuzo
- Department of Otorhinolaryngology, National Medical Center Hospital
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- FURUUCHI Ichiro
- Department of Otorhinolaryngology, Dokkyo University School of Medicine
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- BABA Kotaro
- Department of Otorhinolaryngology, Dokkyo University School of Medicine
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- KANZAKI Hitoshi
- Department of Otorhinolaryngology, Keio University School of Medicine
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- MIYAKE Hirosato
- Department of Otorhinolaryngology, Tokai University, School of Medicine
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- SAKAI Makoto
- Department of Otorhinolaryngology, Tokai University, School of Medicine
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- TAKEYAMA Isamu
- Department of Otorhinolaryngology, St. Marianna Univerisity School of Medicine
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- KAWAMURA Shozo
- Department of Otorhinolaryngology, Juntendo Unviversity, School of Medicine
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- ICHIKAWA Ginichiro
- Department of Otorhinolaryngology, Juntendo Unviversity, School of Medicine
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- SUGITA Rinya
- Department of Otorhinolaryngology, Juntendo Unviversity, School of Medicine
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- OKAMOTO Michiya
- Department of Otorhinolaryngology, Showa University School of Medicine
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- KUBOTA Tetsuaki
- Department of Otorhinolaryngology, Showa University School of Medicine
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- SHIMADA Sanae
- Department of Otorhinolaryngology, Nippon Medical School
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- OGURA Shuji
- Department of Otorhinolaryngology, Japan Red Cross Medical Center
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- IWAMURA Shinobu
- Department of Otorhinolaryngology, Mitsui Memorial Hospital
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- NAGAKURA Kotaro
- Department of Otorhinolaryngology, Doai Memorial Hospital
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- KAWAKUBO Jun
- Department of Otorhinolaryngology, Kosei-Chuo Hospital
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- SAKAMOTO Yutaka
- Department of Otorhinolaryngology, Kawasaki, City Hospital
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- HOMMURA Yoshio
- Department of Otorhinolaryngology, Kawasaki, City Hospital
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- ORIGUCHI Takeshi
- Department of Otorhinolaryngology, Matsumoto National Hospital
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- SHIRAISHI Teruo
- Department of Otorhinolaryngology, Seirei Hamamatsu Hospital
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- TSUKIYAMA Akio
- Department of Otorhinolaryngology, Tokai Teishin Hospital
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- SEKIYA Tadao
- Department of Otorhinolaryngology, Nagoya National Hospital
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- OTSUKA Motoi
- Department of Otorhinolaryngology, Nagoya National Hospital
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- MIYAZAKI Tameo
- Department of Otorhinolaryngology, Faculty of Medicine, Kanazawa University
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- HORIKAWA Toshihiko
- Department of Otorhinolaryngology, Faculty of Medicine, Kanazawa University
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- SATO Kiichi
- Department of Otorhinolaryngology, Kanazawa Medical University
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- NOGAKI Toshiyuki
- Department of Otorhinolaryngology, Toyama Prefectural Central Hospital
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- MIZUKOSHI Osamu
- Department of Otorhinolaryngology, Kyoto Prefectural University of Medicine
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- INOUE Seiji
- Department of Otorhinolaryngology, Kyoto Prefectural University of Medicine
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- NISHIMURA Takeshige
- Department of Otorhinolaryngology, Kyoto First Red Cross Hospital
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- DATE Keiichi
- Department of Otorhinolaryngology, Kyoto First Red Cross Hospital
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- KAWAMOTO Satoshi
- Department of Otorhinolaryngology, Kyoto First Red Cross Hospital
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- NAKAMURA Akimasa
- Department of Otorhinolaryngology, Kyoto Second Red Cross Hospital
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- OKAMOTO Yasuhiko
- Department of Otorhinolaryngology, Kyoto Second Red Cross Hospital
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- TADAKI Nobukazu
- Department of Otorhinolaryngology, Kyoto City Hospital
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- TAKENOUCHI Satoshi
- Department of Otorhinolaryngology, Kuramaguchi Hospital
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- SAKAGUCHI Fumi
- Department of Otorhinolaryngology, Fukuchiyama National Hospital
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- HIRASUGI Yoshiaki
- Department of Otorhinolaryngology, Maizuru National Hospital
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- YOSHIOKA Yoshiko
- Department of Otorhinolaryngology, Maizuru National Hospital
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- NAITOH Toshi
- Department of Otorhinolaryngology, Medical School, Osaka University
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- MATSUNAGA Tooru
- Department of Otorhinolaryngology, Medical School, Osaka University
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- IIDA Masao
- Department of Otorhinolaryngology, Suita City Hospital
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- ITOH Hiroshi
- Department of Otorhinolaryngology, Osaka, Rosai Hospital
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- OKUMURA Shinichi
- Department of Otorhinolaryngology, Osaka, Rosai Hospital
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- YAMAMOTO Kaoru
- Department of Otorhinolaryngology, Osaka City University Medical School
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- YAMAZAKI Taro
- Department of Otorhinolaryngology, Osaka City University Medical School
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- ORITA Yozo
- Department of Otorhinolaryngology, Kawasaki Medical School
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- KASAI Hideo
- Department of Otorhinolaryngology, Kawasaki Medical School
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- KUROZUMI Shizuyuki
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- HARADA Yasuo
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- SUGIMOTO Yoshiro
- Department of Otorhinolaryngology, Hiroshima University, School of Medicine
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- HORI Tlatsuo
- Department of Otorhinolaryngology, Fukuyama National Hospital
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- KUROKAWA Hiroyoshi
- Department of Otorhinolaryngology, Fukuyama National Hospital
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- TAKEBAYASHI Shubun
- Department of Otorhinolaryngology, Onomichi General Hospital
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- HARADA Takashi
- Department of Otorhinolaryngology, Mitsubishi Mihara Hospital
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- YAJIN Koji
- Department of Otorhinolaryngology, Futami-Chuo Hospital
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- HAYASHI Takaharu
- Department of Otorhinolaryngology, Hiroshima Prefectural Hospital
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- NODA Masuhiro
- Department of Otorhinolaryngology, Hiroshima Prefectural Hospital
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- YASHIKI Takeo
- Department of Otorhinolaryngology, Hiroshima Kinen Hospital
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- ASANO Shozo
- Department of Otorhinolaryngology, Matsuyama Red Cross Hospital
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- NIKI Hiroshi
- Department of Otorhinolaryngology, School of Medicine, Tokushima University
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- SHIZUKU Shunichi
- Department of Otorhinolaryngology, School of Medicine, Tokushima University
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- OKADA Shuji
- Dapartment of Otorhinolaryngology, Tokushima Prefectural Central Hospital
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- MATSUURA Kenjiro
- Department of Otorhinolaryngology, Oe-Kyodo Hospital
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- ISHIDA Yoshio
- Department of Otorhinolaryngology, Takamatsu City Hospital
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- MURATA Yoshiharu
- Department of Otorhinolaryngology, Kyushu Welfare Pension Hospital
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- HIROTO Ikuichiro
- Department of Otorhinolaryngology, Kyushu University
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- MORIMITSU Tamotsu
- Department of Otorhinolaryngology, Kyushu University
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- MATSUMOTO Ichiro
- Department of Otorhinolaryngology, Kyushu University
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- HAYASHIDA Kunihiko
- Department of Otorhinolaryngology, Kyushu University
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- HARADA Yoshio
- Department of Otorhinolaryngology, National Fukuoka Central Hospital
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- NISHIDA Yukiaki
- Department of Otorhinolaryngology, Hamanomachi Hospital
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- OCHIAI Yoichiro
- Department of Otorhinolaryngology, Minamata City Hospital
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- MATSUMURA Masumi
- Department of Otorhinolaryngology, School of Medicine, Kagoshima University
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- KIJIMA Tokuaki
- Department of Otorhinolaryngology, School of Medicine, Kagoshima University
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- TANAKA Tsuneo
- Department of Health Administration, School of Health Sciences, Faculty of Medicine
Bibliographic Information
- Other Title
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- 慢性化膿性中耳炎に対するPipemidic acidの薬効評価
- Aminobenzyl penicillinとの二重盲検比較試験による検討
Search this article
Abstract
A multi-clinical, double blind controlled study was carried out to evaluate objectively the efficacy of pipemidic acid (PPA) on chronic suppurative otitis media using aminobenzyl penicillin (ABPC) as the standard drug. The following conculusions were obtained.<BR>1) In the cases of single infections due to GNB, PPA was significantly superior to ABPC in regards of overall clinical efficacy judged by the doctor and committee, and utility judged by the doctor.<BR>2) Moreover, in the same cases as described above, PPA was significantly superior to ABPC in point of elimination of GNB isolated from otorrhea and disappearance of otorrhea.<BR>3) PPA tended to be more effective than ABPC in regards of infections due to Pseudomonas, although there was no significant difference between both the groups.<BR>4) Frequency of side effects was no significant difference between both the groups. But, frequency of allergic symptoms such as eruption in ABPC group was significantly higher that that of PPA.
Journal
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- OTOLOGIA FUKUOKA
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OTOLOGIA FUKUOKA 23 (6), 807-827, 1977
JIBI TO RINSHO KAI
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Details 詳細情報について
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- CRID
- 1390001205495653376
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- NII Article ID
- 130004132771
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- ISSN
- 04477227
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed