COMPARATIVE STUDIES ON ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CAUSATIVE ORGANISMS ISOLATED FROM URINARY TRACT INFECTIONS (1987)
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- KOSAKAI NOZOMU
- Juntendo University Urayasu Hospital
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- KUMAMOTO YOSHIAKI
- Department of Urology, Sapporo Medical College
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- HIROSE TAKAOKI
- Department of Urology, Sapporo Medical College
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- TANAKA NORIAKI
- Department of Urology, Sapporo Medical College
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- HIKICHI YOSHINAO
- Katta Polyclinic Hospital
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- SHIGETA SHIRO
- Department of Bacteriology, Fukushima Medical College
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- SHIRAIWA YASUO
- Department of Urology, Fukushima Medical College
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- YOSHIDA HIROSHI
- Clinical Laboratories, Fukushima Medical College
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- OGATA MASAHIRO
- Clinical Laboratories, Fukushima Medical College
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- TAZAKI HIROSHI
- Department of Urology, School of Medicine, Keio University
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- IRI HISAMI
- Clinical Laboratories, School of Medicine, Keio University
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- UCHIDA HIROSHI
- Clinical Laboratories, School of Medicine, Keio University
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- KOBAYASHI YOSHIO
- Clinical Laboratories, School of Medicine, Keio University
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- MATSUDA SEIJI
- Department of Gynecology, Koto Hospital
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- KITAGAWA RYUICHI
- Department of Urology, Juntendo University School of Medicine
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- FUJITA KAZUHIKO
- Department of Urology, Juntendo University School of Medicine
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- HAYASHI YASUYUKI
- Department of Clinical Pathology, Juntendo University School of Medicine
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- OGURI TOYOKO
- Clinical Laboratories, Juntendo University Hospital
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- FURUSAWA TARO
- Department of Urology, Kyoto Second Red Cross Hospital
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- TAKEUCHI YASUKO
- Clinical Laboratories, Kyoto Second Red Cross Hospital
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- MORIYAMA HIROMI
- Clinical Laboratories, Kyoto Second Red Cross Hospital
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- SHIBATA KIKUTARO
- Clinical Laboratories, Kyoto Second Red Cross Hospital
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- YONEZU SEIBUN
- The First Department of Internal Medicine, Kansai Medical University
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- TAKAHA MINATO
- Department of Urology, Osaka National Hospital
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- MATSUMIYA KIYOMI
- Department of Urology, Osaka National Hospital
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- TANAKA MICHIO
- Clinical Laboratories, Osaka National Hospital
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- YAMAGUCHI KEIZO
- Clinical Laboratories, School of Medicine, Nagasaki University
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- TATEDA KAZUHIRO
- Clinical Laboratories, School of Medicine, Nagasaki University
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- MOCHIDA CHIKAKO
- Clinical Laboratories, School of Medicine, Nagasaki University
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- IGARI JUN
- Department of Clinical Pathology, School of Health Science, Faculty of Medicine, University of Ryukyus
Bibliographic Information
- Other Title
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- 尿路感染症分離菌に対する経口並びに注射用抗菌・抗生剤の抗菌力比較 (第9報1987年)
- III. SECULAR CHANGES IN SUSCEPTIBILITY
- その3.感受性の推移
Abstract
Sensitivity spectra of major species of bacteria (namely Escherichia coli, Klebsiella spp., Proteus spp., Citrobacter spp., Enterobacter spp., Serratia marcescens and Pseudomonas aeruginosa) which were among the clinical isolates mentioned in the first and second reports to various antibacterial and antibiotic agents and time courses of the spectra are reported below.<BR>1. E. coli was sensitive to cefmenoxime (CMX), latamoxef (LMOX), ceftazidime (CAZ), cefzonam (CZON) and flomoxef (FMOX) which are third generation cephems, carumonam (CRMN) which is a monobactam, imipenem (IPM) which is a carbapenem, ofloxacin (OFLX) and ciprofloxacin (CPFX) which are new quinolones. Compared to the preceding 5-year period, sensitivities to most drugs have increased.<BR>2. Klebsiella spp. were sensitive to CMX, CZON and FMOX which are third generation cephem antibiotics, CRMN which is a monobactam and gentamicin (GM) and arbekacin (HBK) which are aminoglycosides. Compared to the preceding 5-year period, the sensitivity on the whole has increased slightly.<BR>3. Proteus spp. were sensitive to CMX, LMOX, CAZ and CZON which are third generation cephems, CRMN, a monobactam and OFLX and CPFX which are new quinolones. Compared to the preceding 5-year period, increased sinsitivities, particularly to parenteral cephems, were found.<BR>4. Citrobacter spp. were sensitive to CPFX which is a new quinolone antibiotic and CRMN, a monobactam. Compared to the preceding 5-year period, the sensitivity as a whole increased but there were still strains against which cefotiam, cefmetazole and, cefoperazone (CPZ) showed high MIC values.<BR>5. Enterobacter spp. were sensitive to OFLX and CPFX, which are new quinolones, IPM, a carbapenem, and GM and HBK which are aminoglycosides. Compared to other bacteria, bacteria of this group were less sensitive to CPZ, CAZ, CZON, and FMOX which are third generation cephems. Compared to the preceding 5-year period, slight increases in sensitivity were found in cases of simple urinary tract infections.<BR>6. S. marcescens as a whole was not very sensitive to antibiotics tested. Compared to the preceding 5-year period, sensitivities to CRMN and minocycline improved slightly.<BR>7. P. aeruginosa was not very sensitive to any drug, as other bacteria were. Compared to the preceding 5-year period, sensitivities to new quinolones OFLX and CPFX and carbapenem IPM decreased slightly.
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 43 (6), 968-1136, 1990
Japan Antibiotics Research Association