CLINICAL STUDIES ON CEFUZONAM IN THE FIELD OF OBSTETRICS AND GYNECOLOGY

  • TATENO MASAYA
    Department of Obstetric and Gynecology, Toyama Prefectural Central Hospital

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Other Title
  • Cefuzonamの産婦人科領域における応用

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In gynecological infections, especially intrapelvic infections, it is sometimes difficult to identify causal microorganisms. In those cases, it becomes a hard task to select most effective antibiotics, hence the use of wide-spectrum antibiotics becomes necessary.<BR>We recently had opportunities to clinically use cefuzonam (CZON, L-105) which has a wide range of spectrum against various bacteria including Staphylococcus aureus, Escherichia coli, Grampositive and Gram-negative anaerobes, etc. The following is a summary of the clinical results:<BR>1. In 7 cases of gynecological infections CZON was evaluated “excellent” in 1 case and “good” in 6 cases, thus the efficacy rate was 100%.<BR>2. Against intrauterine infection caused by S. aureus, “excellent” effect was observed.<BR>3. No sign of side effects was noted in any of the cases.<BR>4. In 1 case, slight elevations of S-GOT and S-GPT were recorded but the elevations were transient.

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