COMPARATIVE STUDIES ON ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CAUSATIVE ORGANISMS ISOLATED FROM PATIENTS WITH URINARY TRACT INFECTIONS (1995)
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- KUMAMOTO YOSHIAKI
- Department of Urology, Sapporo Medical University, School of Medicine
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- TSUKAMOTO TAIJI
- Department of Urology, Sapporo Medical University, School of Medicine
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- HIROSE TAKAOKI
- Department of Urology, Sapporo Medical University, School of Medicine
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- YOKOO AKIFUMI
- Department of Urology, Sapporo Medical University, School of Medicine
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- HIKICHI YOSHINAO
- Katta Polyclinic Hospital
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- SHIGETA SHIRO
- Department of Bacteriology, Fukushima Medical College
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- TAKAHASHI TOSHIMITSU
- Department of Bacteriology, Fukushima Medical College
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- SHIRAIWA YASUO
- Department of Urology, Fukushima Medical College
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- OGIWARA MASAHIKO
- Department of Urology, Fukushima Medical College
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- YOSHIDA HIROSHI
- Department of Clinical Laboratory Medicine, Fukushima Medical College
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- IMAFUKU YUUJI
- Department of Clinical Laboratory Medicine, Fukushima Medical College
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- MURAI MASARU
- Department of Urology, School of Medicine, Keio University
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- WATANABE KIYOAKI
- Central Clinical Laboratories, School of Medicine, Keio University
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- UCHIDA HIROSHI
- Central Clinical Laboratories, School of Medicine, Keio University
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- KOBAYASHI YOSHIO
- Central Clinical Laboratories, School of Medicine, Keio University
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- MATSUDA SEIJI
- Department of Gynecology, Koto Hospital
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- FUJIME MAKOTO
- Department of Urology, Juntendo University, School of Medicine
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- FUJITA KAZUHIKO
- Department of Urology, Juntendo University, School of Medicine
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- IGARI JUN
- Department of Clinical Pathology, Juntendo University, School of Medicine
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- OGURI TOYOKO
- Central Clinical Laboratories, Juntendo University
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- KOSAKAI NOZOMU
- Juntendo University Urayasu Hospital
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- YAMAGUCHI KEIZO
- The First Department of Laboratory, School of Medicine, Toho University Ohmori Hospital
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- MATSUMOTO TETSUYA
- The First Department of Laboratory, School of Medicine, Toho University Ohmori Hospital
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- KASHITANI FUSAKO
- The First Department of Laboratory, School of Medicine, Toho University Ohmori Hospital
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- OOE HIROSHI
- Department of Urology, Kyoto Second Red Cross Hospital
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- MAEKAWA MIKIO
- Department of Urology, Kyoto Second Red Cross Hospital
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- NISHIKAWA MINEKO
- Department of Clinical Laboratory, Kyoto Second Red Cross Hospital
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- YONEZU SEIBUN
- The First Department of Internal Medicine, Kansai Medical University
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- YAMANAKA YOSHITAKA
- The First Department of Internal Medicine, Kansai Medical University
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- OKA TOSHITSUGU
- Department of Urology, Osaka National Hospital
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- TAKANO YUUJI
- Department of Urology, Osaka National Hospital
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- MIYAGAWA YASUSHI
- Department of Urology, Osaka National Hospital
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- TANAKA MICHIO
- Clinical Laboratories, Osaka National Hospital
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- KAKU MITSUO
- Department Laboratory, School of Medicine, Nagasaki University
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- HIRAGATA YOUICHI
- Department Laboratory, School of Medicine, Nagasaki University
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- YOSHIDA RYOUJI
- Department Laboratory, School of Medicine, Nagasaki University
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- MOCHIDA CHIKAKO
- Department Laboratory, School of Medicine, Nagasaki University
Bibliographic Information
- Other Title
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- 尿路感染症分離菌に対する経口並びに注射用抗菌薬の抗菌力比較(第17報1995年)
- III. DIFFERENCES IN SUSCEPTIBILITIES FROM PREVIOUS YEARS
- その3. 感受性の推移
Abstract
Susceptibilities to various antimicrobial agents were examined for Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Klebsiella spp. and Pseudomonas aeruginosa that were isolated from patients with urinary tract infections (UTIs) in 11 hospitals during June, 1995 through May, 1996, and the results were compared with those obtained during the same period in earlier years.<BR>1. Macrolide resistant E. faecalis isolated from uncomplicated UTIs during the latest study period appeared to have increased compared to those in previous study periods. More than 50% of the isolated E. faecalis during the latest study period were resistant to macrolide antibiotics, for the first time in our history.<BR>2. No obvious changes were observed through the years for susceptibilities of S. aureus to various antimicrobial agents. Vancomycin (VCM) showed the highest activity against S. aureus, with MICs below 2μg/ml or below.<BR>3. Among E. coli strains, those with low susceptibilities to quinolones appeared to have increased over the years with MIC90 changed from between 0.125μg/ml or below and 0.5μg/ml in the 1989-1990 period to between 8μg/ml and 128μg/ml in the latest study period.<BR>4. Klebsiella spp. showed higher resistance to most antimicrobial agents during periods of 1993-1994 and 1994-1995, but somewhat lower resistance during period of 1995-1996. No resistant Klebsiella spp. were detected from uncomplicated UTIs during the latest study period.<BR>5. Among P. aeruginosa isolates from complicated UTIs, resistance isolates to gentamicin appeared to be increasing over the years. Resistant strains to quinolones were isolated at lower frequencies during periods of 1991-1994, but higher frequency was observed in the latest period, and MIC50s were between 0.5 and 4μg/ml during 1991-1994, but were 16-32μg/ml during 1995-1996.<BR>These susceptibility changes should be utilized in determining clinical treatments.
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 50 (4), 306-410, 1997
Japan Antibiotics Research Association