Emetic Responses of <I>Sorex unguiculatus</I>

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  • MATSUKI Norio
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • TORII Yoshifumi
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • KAJI Takahide
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • NISHIYAMA Nobuyoshi
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • ISHIYAMA Jun-ichi
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • CHIDA Noboru
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>
  • SAITO Hiroshi
    <I>Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo</I>

Bibliographic Information

Other Title
  • オオアシトガリネズミの嘔吐反応
  • オオアシトガリネズミの嘔吐反応〔英文〕
  • オオアシトガリネズミ ノ オウト ハンノウ エイブン

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Abstract

We have shown previously that Suncus murinus, a species of the insectivore, can vomit in response to various emetogenic stimuli. In the present study we investigated whether or not Sorex unguiculatus, which belongs to different subfamily (Soricinae) of insectivore, vomits in response to emetogenic drugs. Subcutaneous injection of veratrine and oral administration of copper sulfate caused emesis in the animal. Histological study showed that bilateral structure of the area postrema was not importnat for the emetic reflex. Therefore, the capability of emesis may be common to the family of soricidae of the insectivore, and the Sorex unguiculatus is the smallest known mammal which can vomit.

Journal

  • Experimental Animals

    Experimental Animals 42 (2), 225-228, 1993

    Japanese Association for Laboratory Animal Science

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