“NEOCEADER” CONTAINS NICOTINE. A REPORT OF TWO USER'S NICOTINE ADDICTION

DOI Web Site 4 References
  • TANAKA Hideo
    Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases.
  • NOGAMI Hiroshi
    Osaka Prefectural Institute of Public Health
  • NAKAGAWA Hidekazu
    Shuso Municipal Hospital
  • HASUO Seiko
    Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases.

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Other Title
  • ネオシーダーのニコチン含有状況から見た医薬品としての妥当性の検討
  • ネオシーダーのニコチン含有状況からみた医薬品としての妥当性の検討
  • ネオシーダー ノ ニコチン ガンユウ ジョウキョウ カラ ミタ イヤクヒン ト シテ ノ ダトウセイ ノ ケントウ

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Description

“Neoceader smoking” is widely marketed in drug stores as an over the counter expectorant for cigarette smokers in Japan. Using high-pressure liquid chromatography, we determined that one piece of Neoceader (3 cm) contains 0.79 mg of nicotine, which is equivalent to one-sixth of the amount of nicotine in one Japanese cigarette (Mildseven extra-light, Mildseven super-light, or Sevenstar). Two patients who had switched from cigarette smoking to Neoceader smoking, subsequently became addicted to nicotine. The cotinine concentration in their urine were 937 ng/ml and 2,724 ng/ml, respectively. These findings demonstrate that Neoceader contains nicotine and that its use can lead to nicotine addiction.

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