慢性副鼻腔炎に対するロキシスロマイシン少量長期投与

書誌事項

タイトル別名
  • A Long-Term Low-Dose Roxithromycin Therapy for Chronic Sinusitis

説明

Twenty patients with chronic sinusitis were given one tablet (150 mg) of roxithromycin (RXM) once a day for three months. Rates of improvement of subjective symptoms (disappearance or improvement) after the three-month therapy were: nasal obstruction 92.3% nasal dripping 81.25%, postnasal dripping 94.4%, sensation of foul odor 100.0%, and headache and dull headache 90.0%. Objective findings improved as follows: flare of the nasal mucosa 80.0%, edema and swelling of the nasal mucosa 85.0%, volume of nasal discharge 90.0%, property of nasal discharge 95.0%, and volume of postnasal dripping 87.5%. Average score of the subjective symptoms and objective findings in ten areas were significantly lowered after three-months of RXM therapy compared with those before therapy. Many aspects of the nonantibacterial actions considered inherent in RXM remain obscure, but this long-term, low-dose RXM therapy seemed to be effective in treating chronic sinusitis.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390001205527501696
  • NII論文ID
    130004683627
  • DOI
    10.5631/jibirinsuppl1986.1993.supplement64_119
  • ISSN
    09121870
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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