書誌事項
- タイトル別名
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- Establishment of a Human Rectal Cancer
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A permanent cell line (S-7512) was established by cell culture from the subcutaneous metastatic tumor of a human rectal cancer and has been maintained for 18 months. Cultured cells grew as isolated and piled-up colonies of epithelial cells, each with a scanty cytoplasm and a large nucleus containing several nucleoli. The average doubling time of this cell line was 57hr and plating efficiency was 30.1∼45.2% in a liquid medium. The modal chromosome number was 115 but a marker chromosome was not evident. Electron microscopic examination revealed many microvilli, free ribosomes, and abundant glycogen granules. Heterotransplantation of the cultured cells produced a large tumor and its microscopic examination showed the same histological appearance as the original tumor (carcinoma simplex). Carcinoembryonic antigen level of the spent medium of the confluent culture was 235.50ng/3.2×106 cells.
収録刊行物
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 68 (6), 775-780, 1977
日本癌学会
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詳細情報 詳細情報について
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- CRID
- 1390001205529339008
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- NII論文ID
- 130006409787
- 40000528960
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- NII書誌ID
- AN00045888
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- NDL書誌ID
- 1917530
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- ISSN
- 0016450X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可