ISOLATION AND CHARACTERIZATION OF HIGH AND LOW DIFFERENTIATION-INDUCIBLE FRIEND LEUKEMIA LINES

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説明

Induction of erythrodifferentiation was carried out by addition of dimethyl sulfoxide or butyric acid to the culture medium among 80 subclones of T-3-Cl-2 Friend mouse leukemia line. Hemoglobin-positive cells were counted on day 5 of the inducer treatment on the hemocytometer after benzidine staining. Some cell lines were inducible by both of the inducers, but others were insensitive to dimethyl sulfoxide, but sensitive to butyric acid. Eight characteristic T-3-Cl-2 subclones have been selected; 2 highly inducible, 2 moderately inducible, and 4 minimally inducible. The data of differentiation inducibility together with the history of the T-3-Cl-2 line may facilitate extensive application of the T-3-Cl-2 system.

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詳細情報 詳細情報について

  • CRID
    1390001205529645696
  • NII論文ID
    130006409622
  • DOI
    10.20772/cancersci1959.67.5_767
  • ISSN
    0016450X
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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