SYNTHESIS OF 4-(N-HYDROXY-N-METHYLAMINO) QUINOLINE 1-OXIDE AND ITS CARCINOGENIC ACTIVITY ON MICE
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- KAWAZOE Yutaka
- Faculty of Pharmaceutical Sciences, Nagoya City University
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- OGAWA Osamu
- Faculty of Pharmaceutical Sciences, Nagoya City University
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- TAKAHASHI Kazuhiko
- Faculty of Pharmaceutical Sciences, Nagoya City University
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- SAWANISHI Hiroyuki
- Faculty of Pharmaceutical Sciences, Hokuriku University
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- ITO Nobuyuki
- First Department of Pathology, Nagoya City University Medical School
Bibliographic Information
- Other Title
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- Synthesis of 4 N Hydroxy N methylamino
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Abstract
4-(N-Hydroxy-N-methylamino) quinoline 1-oxide (N-Me-4-HAQO), the structure of which consists of a quinoline 1-oxide moiety involved in carcinogenic 4-nitroquinoline 1-oxide and an N-hydroxy-N-methylamino group involved in N-hydroxy-N-monomethylaminoazobenzene, was sythesized and proved to be potently carcinogenic in mice by its subcutaneous injection.
Journal
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 69 (6), 835-837, 1978
The Japanese Cancer Association
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Details 詳細情報について
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- CRID
- 1390001205530075776
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- NII Article ID
- 40000529308
- 130006409853
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- NII Book ID
- AN00045888
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- NDL BIB ID
- 2075754
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- ISSN
- 0016450X
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed