An experimental study on the SN2 reaction pathway of acyl derivatives

DOI

Bibliographic Information

Other Title
  • アシル化合物のSN2反応の機構に関する実験的研究

Description

SN2 reactions of compounds which have a carbonyl group at the alpha position are known to be accelerated compared with the reactions of simple alkyl substrates. To clarify the origin of the acceleration experimentally, the reaction of phenacyl chloride and sodium hydroxide was studied. When these two compounds were mixed at room temperature, alpha-hydroxyacetophenone was obtained and then the reaction yielded benzoic acid. The reaction pathway of the benzoic acid generation will be discussed.

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Keywords

Details 詳細情報について

  • CRID
    1390001205556411264
  • NII Article ID
    130004645004
  • DOI
    10.11494/kisoyuki.18.0.245.0
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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