3D Numerical Simulation of Growing Cancer and Angiogenic Blood Vessel Network Using a Particle Model

DOI

Bibliographic Information

Other Title
  • 腫瘍の成長と血管新生の粒子モデルによる3次元数値解析

Description

Between tumor growth and angiogenesis are closely related. While the blood vessels supply nutrition to support growth of cancer cells, cancer cells induces blood vessels simultaneously. Thus they grow by interacting each other. As the tumor is difficult to observe, clarifying the phenomenon using numerical simulation is desired. In this study, a three-dimensional particle model is introduced to simulate the growth of cancer cells and angiogenesis and to analyze the relationship between them. The analysis confirmed the growth of the tumor vascular network formed with the growth of cancer cells. Adding the assumptions on the effect of the internal pressure, blood vessel network was confirmed to be formed near the tumor surface.

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Details 詳細情報について

  • CRID
    1390001205593172352
  • NII Article ID
    130004604826
  • DOI
    10.11345/japannctam.60.0.266.0
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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