Comparison of malaria gameto’s exflagellation inducing factor in the salivary glands of five mosquito species

DOI
  • Wang J
    Department of Medical Zoology, Jichi Medical School
  • Hirai M
    Department of Medical Zoology, Jichi Medical School
  • Yoshida Y
    Department of Medical Zoology, Jichi Medical School
  • Arai M
    Department of Medical Zoology, Jichi Medical School
  • Ishii A
    Department of Medical Zoology, Jichi Medical School
  • Matsuoka H
    Department of Medical Zoology, Jichi Medical School

Bibliographic Information

Other Title
  • 5種の蚊の唾液腺におけるマラリア生殖体鞭毛放出誘導因子の比較

Description

Malaria gametocytes undergo gamete formation in mosquito midgut within minutes after ingestion of infected bloodmeal. Male gametogenesis (exflagellation) of Plasmodium berghei, a rodent malaria parasite, can be induced in vitro by the combination of a reduction in temperature (from 37C to 21C) and a simultaneous pH rise (from 7.3 to 8.0). We have reported the existence of exflagellation inducing factor (EIF) in the salivary glands of Ahopheles stephensi (Hirai et al., 2001), which induces exflagellation at a non-permissive pH. We examined for EIF in the salivary glands of four other species, An omorii, Aedes aegypti, Ae albopictus and Culex pipiens pallens. As the results, all the mosquito species examined contained EIF in the salivary glands. An stephensi and An omorii significantly consumed EIF after blood feeding compared with the other species. This indicate that EIF in the salivary glands of Anopheles spp is taken into the midgut more than the other species. It would be one of the reasons why only anopheline mosquito can transmit malaria parasites.

Journal

Details 詳細情報について

  • CRID
    1390001205622706688
  • NII Article ID
    130006982819
  • DOI
    10.11536/jsmez.54.0.9.0
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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