Gene Co-expression Network Analysis of Amino Acid Metabolism Genes
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- Sugiyama Kenjiro
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Hirai Masami
- Plant Science Center, RIKEN
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- Ogata Yoshiyuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Sakurai Nozomu
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Aoki Koh
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Sawada Yuji
- Plant Science Center, RIKEN
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- Tohge Takayuki
- Plant Science Center, RIKEN
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- Suzuki Hideyuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Saito Kazuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst. Plant Science Center, RIKEN Graduate School of Pharmaceutical Science, Chiba Univ.
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- Shibata Daisuke
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
Bibliographic Information
- Other Title
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- アミノ酸代謝系遺伝子群の発現相関ネットワーク解析
Abstract
Analysis of gene co-expression network can facilitate characterization and prediction of gene functions. We analyzed a mutual relationship between genes involved in amino acid biosynthesis using co-expression network constructed from publicly available correlation coefficient data of Arabidopsis (ATTED-II). The genes were clustered into three co-expressed groups. Group 1 contained the genes involved in valine, leucine, and isoleucine biosynthesis. Group 2 contained genes involved in arginine biosynthesis. Group 3 contained genes involved in glutamine, glutamate, serine, and glycine biosynthesis. We analyzed the co-expression patterns of the genes in each group with genes that were not directly involved in amino acid biosynthetic pathways. The result demonstrated the presence of the genes that could related the expression of amino acid biosynthesis genes. We are currently making overexpressors of these candidate genes in Arabidopsis T87 culture cells, and effects on the transcript and metabolite accumulation will be discussed.
Journal
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- Plant and Cell Physiology Supplement
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Plant and Cell Physiology Supplement 2006 (0), 108-108, 2006
The Japanese Society of Plant Physiologists
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Details 詳細情報について
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- CRID
- 1390001205628889856
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- NII Article ID
- 130006989228
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed