Elucidation of regulatory network for isoprenoid biosynthesis using correlation coefficients from microarray expression data
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- Sano Ryosuke
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Ogata Yoshiyuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Sakurai Nozomu
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Aoki Koh
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Suzuki Hideyuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
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- Saito Kazuki
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst. Graduate School of Pharmaceutical Sciences, Chiba Univ.
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- Shibata Daisuke
- The NEDO Team of Applied Plant Genomics, Kazusa DNA Res. Inst.
Bibliographic Information
- Other Title
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- イソプレノイド合成経路の制御系の解明にむけた発現相関のネットーワーク解析
Abstract
We investigated the regulatory mechanisms of isoprenoid biosynthesis, especially with reference to cis-prenyltransferase (cPT) which is involved in rubber synthesis. By analyzing co-expression of isoprenoid biosynthesis genes using the correlation coefficients calculated from 771 AtGenExpress data, some gene networks are inferred. 1) Genes in methylerythritol phosphate (MEP) pathway were closely connected, whereas those of mevalonate (MVA) pathway were only clustered when using the categorized array data from tissues. 2) Phosphomevalonate kinase gene was constantly isolated from the cluster of mevalonate pathway genes owing to its constitutive high expression. 3) Using the tissue-categorized array data each cPT gene was not connected with other cPT genes or the isoprenoid biosynthesis genes, but connected with some transcription factor genes. <br>For candidate transcription factors for cPT, generation of transgenic lines with overexpression or RNAi construct is in progress.
Journal
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- Plant and Cell Physiology Supplement
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Plant and Cell Physiology Supplement 2006 (0), 109-109, 2006
The Japanese Society of Plant Physiologists
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Details 詳細情報について
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- CRID
- 1390001205628891776
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- NII Article ID
- 130006989229
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed