A global approach to predict gene expression networks using Arabidopsis cultured cells
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- Ogata Yoshiyuki
- Kazusa DNA Research Institute
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- Fujii Fumiko
- Kazusa DNA Research Institute
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- Morishita Yoshihiko
- Kazusa DNA Research Institute
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- Matsuura Takashi
- Kazusa DNA Research Institute
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- Mori Kumiko
- Kazusa DNA Research Institute
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- Asami Yuuki
- Kazusa DNA Research Institute
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- Tange Yoshie
- Kazusa DNA Research Institute
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- Motegi Takeshi
- Kazusa DNA Research Institute
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- Hiruta Atsushi
- Kazusa DNA Research Institute
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- Sano Ryosuke
- Kazusa DNA Research Institute
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- Ohno Takashi
- Kazusa DNA Research Institute
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- Ara Takeshi
- Kazusa DNA Research Institute
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- Akimoto Nayumi
- Kazusa DNA Research Institute
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- Nakamura Yukiko
- Kazusa DNA Research Institute
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- Sakurai Nozomu
- Kazusa DNA Research Institute
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- Okazaki Koei
- Kazusa DNA Research Institute
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- Aoki Koh
- Kazusa DNA Research Institute
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- Suzuki Hideyuki
- Kazusa DNA Research Institute
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- Saito Kazuki
- Fac. of Pharm., Chiba Univ. PSC, RIKEN
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- Shibata Daisuke
- Kazusa DNA Research Institute
Bibliographic Information
- Other Title
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- シロイヌナズナ培養細胞を用いた発現制御ネットワーク予測への大規模アプローチ
Abstract
Knowledge on the functions of Arabidopsis genes has been rapidly accumulated, and it is a challenge to reveal the expression system of genes with useful functions. To perform a global approach for obtaining the information on such system, we selected 187 Arabidopsis genes, constructed the T87 cultured cells in which the genes are over-expressed and/or down-regulated by RNA interference, and then executed an analysis based on 214 DNA microarray chips using the cells. In the analysis, the expression value of each gene was standardized. Based on the standardized values, we searched genes that show the expression specific in the cell for an over-expressed or down-regulated gene of interest and then associated the specifically-expressed genes with the gene of interest as candidate regulatory relationships. Using the information of such associations, we depicted a gene regulatory network in a T87 cultured cell.
Journal
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- Plant and Cell Physiology Supplement
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Plant and Cell Physiology Supplement 2009 (0), 0193-0193, 2009
The Japanese Society of Plant Physiologists
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Details 詳細情報について
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- CRID
- 1390001205630409216
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- NII Article ID
- 130006991109
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed