水溶性ビタミン混合剤投与中止1週間後の尿中水溶性ビタミン排泄量

  • 福渡 努
    滋賀県立大学人間文化学部生活栄養学科
  • 柴田 克己
    滋賀県立大学人間文化学部生活栄養学科

書誌事項

タイトル別名
  • Urinary Excretion of Water-Soluble Vitamins One Week After Stopping Administration of the Water-soluble Vitamin Mixture
  • スイヨウセイ ビタミン コンゴウザイ トウヨ チュウシ 1シュウカンゴ ノ ニョウチュウ スイヨウセイ ビタミン ハイセツリョウ

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抄録

The number of people taking large amounts of vitamin supplements is increasing in Japan. Taking large amounts of water-soluble vitamins is not considered risky because excess water-soluble vitamins are quickly excreted in the urine. In the present study, we investigated the clearance of water-soluble vitamins in Japanese. In the first week, six young female subjects ate the diet. In the second week, they ate the same diet with 6 times the recommended water-soluble vitamin dose based on the Dietary Reference Intake (DRI) for Japanese. In the third week, they ate the same diet without the vitamin mixture. The 24-h urine samples were collected every week. All water-soluble vitamins except vitamin B_<12> in 24-h urine samples were measured. The urinary excretion of nicotinamide metabolites, biotin, and ascorbic acid in the third week was same as that in the first week. Urinary thiamin in the third week was 4.4 times higher than in the first week, riboflavin was 3.4 times, vitamin B_6 metabolite 4-pyridoxic acid 2.0 times, pantothenic acid 2.4 times, and folic acid 3.1 times.

収録刊行物

  • ビタミン

    ビタミン 82 (11), 601-606, 2008

    公益社団法人 日本ビタミン学会

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