Different features in ventilatory vs. respiratory sensation response to CO2 with varying PO2

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Other Title
  • 高炭酸と低酸素に対する換気応答と呼吸感覚応答の違い

Abstract

Although respiratory sensation such as dyspnea, or breathlessness are known to be elicited by carbon dioxide, and hypoxia, it is not well known if there is a positive interaction between both chemical stimuli, in the same manner as in ventilation. We examined both ventilation and respiratory sensation during progressive hypoxia with three different CO2 levels using 14 young subjects. Ventilatory variables such as end-tidal CO2 (PetCO2) and O2 (PetO2), tidal volume (VT), respiratory frequency (f) and minute ventilation (VE) were monitored using an aeromonitor (Minato) and the arterial oxygen saturation (SpO2) was by a pulse oxymeter (Ohmeda, Biox). All of these data were stored into a personal computer with breath by breath fashion. We built the model to extract both sensitivities and thresholds of hypercapnia and hypoxic ventilatory responses and the sensitivity of their interaction. [J Physiol Sci. 2008;58 Suppl:S118]

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Details 詳細情報について

  • CRID
    1390001205729538688
  • NII Article ID
    130007039278
  • DOI
    10.14849/psjproc.2008.0.118.1
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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