Impact of Longitudinal Changes in Psoriasis Skin Symptoms on Quality of Life

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  • 乾癬による皮疹がQOLに及ぼす影響―PDI日本語版を用いた男女別の検討―
  • カンセン ニ ヨル ヒシン ガ QOL ニ オヨボス エイキョウ PDI ニホンゴバン オ モチイタ ダンジョ ベツ ノ ケントウ

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Abstract

This study was conducted to determine the impact of longitudinal changes in psoriasis skin symptoms on quality of life (QOL) among patients with psoriasis. Participants were 228 patients diagnosed with psoriasis. Each participant was asked to respond to the same questionnaire twice at 4 month interval. The data from 115 patients was used for analysis. Concerning PDI, significant gender differences of the mean score were demonstrated in areas of “daily activities” and the total score. As for the impact of longitudinal changes in psoriasis symptoms, for male patients the PDI total score was related to the changes of BSA, Self-BSA, PASI, and Self-PASI, whereas for female patients, the PDI total score was related to the change of Self-BSA. For male patients, the severity of the skin symptoms and changes in the skin symptoms were related to PDI, but for female patients, severity of the present skin symptoms was more strongly related to PDI. The findings of this study illustrate the gender differences in the influences of severity and changes in skin symptoms and will contribute to QOL-oriented care of patients with psoriasis.

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