Clinical Significance of Plasma Coagulation Factor XIII in Patients with Anaphylactoid Purpura

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  • アナフィラクトイド紫斑における血液凝固第XIII因子値の臨床的意義
  • アナフィラクトイド紫斑における血液凝固第13因子値の臨床的意義
  • アナフィラクトイド シハン ニ オケル ケツエキ ギョウコ ダイ13 インシチ ノ リンショウテキ イギ

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Abstract

We assessed the scores of plasma coagulation factor XIII in the 21 patients with anaphylactoid purpura of all generations that we have diagnosed at Nippon Medical School Hospital in order to evaluate the significance of plasma coagulation factor XIII in anaphylactoid purpura. We examined a series of 21patients (ten males and eleven females) with anaphylactoid purpura. Eight (38.1%) of them had decreases in score of coagulation factor XIII. Five (62.5%) of them had joint symptoms, and two (25.0%) of them had abdominal symptoms. In the group with low levels of coagulation factor XIII, patients had more frequent and more severel renal abnormalifies, such as hematuria (50.0%) and proteinuria (87.5%). The activity of plasma coagulation factor XIII appears to have a predictive value for renal function in patients with anaphylactoid purpura.

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