A case of Behçet’s disease with an initial onset of thrombophlebitis

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  • Oku Kentaro
    Department of Dermatology, Fukushima Medical University School of Medicine
  • Otsuka Mikio
    Department of Dermatology, Fukushima Medical University School of Medicine
  • Yamamoto Toshiyuki
    Department of Dermatology, Fukushima Medical University School of Medicine

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Other Title
  • 血栓性静脈炎を契機に診断されたBehçet病の1例～当教室におけるBehçet病の初発症状についての検討～
  • 血栓性静脈炎を契機に診断されたBehcet病の1例 : 当教室におけるBehcet病の初発症状についての検討
  • ケッセンセイ ジョウミャクエン オ ケイキ ニ シンダン サレタ Behcetビョウ ノ 1レイ : トウ キョウシツ ニ オケル Behcetビョウ ノ ショハツ ショウジョウ ニ ツイテ ノ ケントウ

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A 27-year-old Japanese female visited our hospital complaining of painful nodules on her bilateral lower legs that appeared 2 months previously. A physical examination showed nail-sized, tender, painful, subcutaneous nodules on her extensor surface of her lower legs. A histopathological examination revealed small vessels in subcutaneous tissue attacked by inflammatory cells composed of neutrophils, lymphocytes, histiocytes, and giant cells. The initial diagnosis was thrombophlebitis, and antithrombogenic agents were started. During the course of follow-up, she developed recurrent oral ulcers, an esophageal ulcer, iliac ulcers and arthritis. Laboratory investigation showed HLA-B51(+) and positive pathergy test. She was diagnosed as having intestinal type of Behçet’s disease. We analyzed the initial symptoms of Behçet’s disease cases diagnosed in our department from 1990 to 2010 and compared them with multinational data.

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