A Japanese Case of Newly-developed Multibacillary Leprosy Initially Diagnosed as Sarcoidosis

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  • サルコイドーシスと診断されていた多菌型ハンセン病の日本人新規発症例
  • 症例報告 サルコイドーシスと診断されていた多菌型ハンセン病の日本人新規発症例
  • ショウレイ ホウコク サルコイドーシス ト シンダン サレテ イタ タキンガタ ハンセンビョウ ノ ニホンジン シンキ ハッショウレイ

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<p>A 74-year-old man born in Osaka is presented. He developed abnormal sensations in the extremities at the age of 65 years, and caused in difficulty in walking around two years later. When he was 70, infiltrative, annular or irregular erythemas appeared on his face and extremities. Based on the histological assessment of a skin biopsy and elevation of serum angiotensin-converting enzyme (ACE) level, he was diagnosed with sarcoidosis at the age of 73. He continued to take oral prednisolone, which had been prescribed for renal dysfunction. During admission to the Neurological Department of Wakayama Medical University at the age of 74 years, he was diagnosed as having multiple mononeuropathy and was referred to the Dermatological Department regarding skin lesions. Skin smears and sections with Fite staining revealed multiple bacilli, leading to a diagnosed of multibacillary leprosy. He also developed lagophthalmos. Multi-drug therapy decreased the number of bacilli in skin smears, but his neurological symptoms and skin lesions gradually got worse as his serum ACE level increasing. Therefore, he was diagnosed with a type 1 leprosy reaction and the dose of oral predonisolone has been increased.</p>

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