A MEDICO-LEGAL STUDY ON THE PREVENTION OF SUDDEN DEATH DUE TO INFECTIOUS DISEASE

  • YONEYAMA Yuko
    Department of Legal Medicine, Showa University School of Medicine
  • SATO Keizo
    Department of Legal Medicine, Showa University School of Medicine
  • KUSHIMA Miki
    Department of Pathology, Showa University Koto Toyosu Hospital
  • KURIHARA Tatsuya
    Department of Hospital Pharmaceutics, Showa University School of Pharmacy
  • FUJISHIRO Masaya
    Department of Legal Medicine, Showa University School of Medicine
  • MIZUNO Shun
    Department of Legal Medicine, Showa University School of Medicine
  • KIMU Sungmi
    Department of Legal Medicine, Showa University School of Medicine
  • SATO Junichi
    Department of Legal Medicine, Showa University School of Medicine
  • NEMOTO Noriko
    Department of Legal Medicine, Showa University School of Medicine
  • LEE Xiao-Pen
    Department of Legal Medicine, Showa University School of Medicine
  • FUKUCHI Urara
    Department of Legal Medicine, Showa University School of Medicine
  • SAWAGUCHI Toshiko
    Department of Legal Medicine, Showa University School of Medicine National Institute of Public Health

Bibliographic Information

Other Title
  • 感染症突然死防止に向けての法医学的検討
  • 感染症突然死防止に向けての法医学的検討 : 感染症突然死剖検例と心臓突然死剖検例との比較をもとに
  • カンセンショウ トツゼンシ ボウシ ニ ムケテ ノ ホウイガクテキ ケントウ : カンセンショウ トツゼンシ ボウケンレイ ト シンゾウ トツゼンシ ボウケンレイ ト ノ ヒカク オ モト ニ
  • ―感染症突然死剖検例と心臓突然死剖検例との比較をもとに―
  • ―BASED ON COMPARISON OF AUTOPSY CASES FOR SUDDEN DEATHS DUE TO INFECTIOUS DISEASES WITH THOSE OF SUDDEN CARDIAC DEATHS―

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Abstract

Sudden deaths are frequently caused by heart or cerebrovascular diseases and infrequently by infectious diseases. There have been only a few reports on investigations involving autopsies of patients with infection as an endogenous cause of sudden death and no reports on the comparison with sudden deaths due to heart diseases. In the present study, sudden deaths due to infectious (15 cases) or heart (45 cases) diseases, which we encountered, were compared their courses leading to death and autopsy findings. The causes of deaths due to infectious diseases (males 8, females 7) included pneumonia (9 cases), pulmonary tuberculosis (4 cases), cholecystitis (1 case), and cystitis (1 case). 8 of the patients were male and 7 female. In a univariate analysis of the sudden deaths due to infectious or heart diseases, the sex, emaciation, conjunctival pallor, cardiac hypertrophy, cardiac dilatation, turtle fat clots, dark red fluidity of heart blood, myocardial fibrosis, hilar lymphadenopathy, multiple organ congestion, gallbladder bulging, gastric emptiness, and infected spleen were extracted as significant factors. In a multivariate analysis, conjunctival pallor, turtle fat clots, myocardial fibrosis, and cardiac hypertrophy were extracted as significant factors for the differential diagnosis of sudden deaths due to infectious and heart diseases. In cases with conjunctival pallor and turtle fat clots at autopsy, sudden death due to infectious diseases should be considered, and foci of infection need to be investigated in detail. In this study, we found that emaciation could cause sudden death due to infectious diseases. An adequate amount of nourishment should be taken to prevent such a death. As most autopsy cases for sudden deaths due to cardiac and infectious diseases revealed atrophy of the adrenal gland, atrophy should be examined by three-dimensional computer tomography. To prevent sudden death, patients with atrophy of the adrenal gland and also suffering from infectious diseases should be treated early.

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