SURVEY ON THE TREATMENT OF OSTEOPOROSIS

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  • NAGAI Takashi
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center
  • KURODA Takuma
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center
  • SAKAMOTO Wakako
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center
  • ISHIKAWA Koji
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center
  • SAKAMOTO Keizo
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center
  • INAGAKI Katsunori
    Department of Orthopaedic Surgery, Showa University School of Medicine<br>Showa University Hospital Orthpaedic Surgery, Osteoporosis Treatment Center

Bibliographic Information

Other Title
  • 骨粗鬆症治療に関する意識調査
  • 骨粗鬆症治療に関する意識調査 : 仮想症例を用いた,アンケート結果
  • コツソショウショウ チリョウ ニ カンスル イシキ チョウサ : カソウ ショウレイ オ モチイタ,アンケート ケッカ
  • ―仮想症例を用いた，アンケート結果―

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Abstract

Therapeutic agents primarily used for osteoporosis include PTH, anti-RANKL, bisphosphonate, and SERM. We investigated the difference between patients with high-risk osteoporosis and those with mild to moderate osteoporosis. In this study, we assessed the responses of nearby physicians in private and public practices, in an awareness survey regarding the diagnosis and treatment selection of osteoporosis. To achieve smooth medical cooperation, this study was aimed to share information of osteoporosis. We presented a hypothetical patient to physicians in private and public practices of our hospital wards and hospital wards in Shinagawa, Meguro, Ota, and Setagaya in Tokyo. Further, these physicians completed an anonymous, written questionnaire designed to survey their awareness of diagnosis and treatment options for osteoporosis. Of the 330 physicians, 143 responded to the questionnaire (response rate: 43.3%). Common imaging tests (in addition to bone densitometry) were thoracolumbar radiography (53%) and bone mineral density measurement of the lumbar spine and/or femur (31%). Physicians who reported that they did not perform further blood and urine testing additionally reported that they included other types of tests. A total of 73% physicians reported that they had measured bone metabolism markers, including (in descending order) TRACP-5b (48%), urinary NTX (41%), and P1NP (27%). With regard to treatment, therapeutic exercise and dietary therapy accounted for 30%～40% of the patients, pharmacotherapy included bisphosphonates (75%) and vitamin D3 (67%). In addition to the inspection items we indicated, we found that diagnosis was based on bone mineral density measurement, and 73% of physicians reported that they would perform additional measurements of bone metabolism markers. Furthermore, all physicians considered initiating osteoporosis therapy, including conservative therapy, for the hypothetical patient based on clinical practice guidelines for osteoporosis and their treatment experience.

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