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- 赤沼 哲史
- 早稲田大学人間科学学術院
書誌事項
- タイトル別名
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- Thermophilicity of early life revealed by comparing extant genomes
- ゲノム ハイレツ ノ ヒカク カラ アキラカ ニ ナッタ ショキ セイメイ ノ コウネッセイ
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<p>Understanding the origin and early evolution of life is fundamental to improve our knowledge on ancient living systems and their environments. Information about the environment of early Earth is sometimes obtained from fossil records. However, no fossil records of ancient organisms that lived more than 3,500 million years ago have been found. Instead, we can now predict the sequences of ancient genes and proteins by comparing extant genome sequences accumulated by the genome project of various organisms. A number of computational studies have focused on ancestral base contents of ribosomal RNAs and the amino acid compositions of ancestral proteins, estimating the environmental temperatures of early life with conflicting conclusions. On the other hand, we experimentally resurrected inferred ancestral amino acid sequences of nucleoside diphosphate kinase that might have existed 3,500–3,800 million years ago. The resurrected proteins are stable around 100℃, being consistent with the thermophilic ancestry of life. Our experimental data do not exclusively indicate the thermophilic origin of life; rather, our conclusion is compatible with the idea that the hyperthermophilic ancestor was selected for increased environmental temperatures of early Earth probably caused by meteorite impacts.</p>
収録刊行物
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- 地球化学
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地球化学 50 (3), 199-210, 2016
一般社団法人日本地球化学会
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詳細情報 詳細情報について
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- CRID
- 1390001205743549696
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- NII論文ID
- 130005267127
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- NII書誌ID
- AN00141280
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- ISSN
- 21885923
- 03864073
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- NDL書誌ID
- 027672000
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
- KAKEN
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- 使用不可