Two cases of lupus-like symptoms associated with human parvovirus-B19 infection

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  • OBINATA KAORU
    Department of Pediatrics, Koshigaya Municipal Hospital Department of Pediatrics, Koshigaya Municipal Hospital

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  • ループス様症状を呈したヒトパルボウイルス-B19感染症の2例

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We report two cases of human parvovirus-B19 infection mimicking systemic lupus erythematosus. Both patients presented with rash, fever, arthritis, cytopenia, hypocomplementemia and positive antinuclear antibodies. These initial manifestrations strongly suggested a diagnosis of systemic lupus erythematosus. However, serologic studies indicated recent human parvovirus-B19 infection. Regression occurred clinically and serologically within one year. It is considered that human parvovirus-B19 infection manifests lupus-like presentation and accompanies a transient autoimmune state.

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