Mechanism of early brain injury after subarachnoid hemorrhage

DOI Web Site Open Access
  • Endo Hidenori
    Department of Neurosurgery, Kohnan Hospital, Miyagi, Japan
  • Tominaga Teiji
    Department of Neurosurgery, Tohoku University Hospital, Miyagi, Japan

Bibliographic Information

Other Title
  • くも膜下出血急性期脳損傷のメカニズム

Search this article

Description

Exact mechanisms of early brain injury after subarachnoid hemorrhage (SAH) is still undetermined. We showed that reduction in oxidative stress may attenuate early brain injury after SAH via activation of Akt/GSK3β survival signaling in rat SAH model. We also showed that diffusion weighted imaging (DWI) is useful tool to detect early brain injury after SAH in the clinical setting. DWI can provide an objective means to estimate the outcome of poor-grade SAH. These research about early brain injury after SAH could provide new therapeutic approach.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top