Usefulness of Endoscopic Iodine Staining Method for Detection of Superficial Esophageal Cancer

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  • Kouda Takahiko
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Yamaki Goro
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Ozaki Tsuyoshi
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Oura Michihisa
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Matsumoto Satoru
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Okura Yasuo
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Shiga Toshiaki
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Nomoto Kazuo
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center
  • Nishizawa Mamoru
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center

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Other Title
  • 上部消化管内視鏡検査時のヨード染色の検討

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Abstract

We compared the depth of superficial esophageal cancer (SEC) and the interval of endoscopic examination with iodine staining method (ISM) . Twelve SEC patients detected with ISM, whose SEC were denied at the previous examination with or without ISM, were divided into two groups. Each group consisted of 6 patients examined with (group A) or without (group B) ISM, respectively.<br> In group A, 5 out of 6 patients had the depth of m1 and one had m3. Average interval of the examination in group A was 29 months (range : 18-36 months) . In contrast with group A, one had the depth of m2 and 5 had the invasion of m3 or submucosa. Average interval was 38 months (range : 14-60 months) in group B.<br> ISM appears to be useful for detection of m1 and m2 which are difficult to find with a conventional endoscopic observation. We recommend ISM at an interval of about 24 months for subjects without unstained area. This should be clarified by a prospective controlled study.

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