Lipoylglutamateの微生物活性

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書誌事項

タイトル別名
  • MICROBIOLOGICAL ACTIVITIES OF LIPOYLGLUTAMATE
  • Lipoylglutamate ノ ビセイブツ カッセイ

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説明

In investigation of the biological activities of some lipoic acid derivative for the growth of Streptococcus faecalis R and Corynebacterium bovis 187,it was found that lipoylglutamate was active for Corynebacterium bovis alone. To clarify this mechanism, the enzymatic activies of extracts obtained from both microbes on lipoylglutamate was studied. Corynebacterium bovis contained an enzyme which liberates lipoic acid from lipoylglutamate, on the other hand no activity of the extracts from Streptococcus faecalis R was found. The enzyme was partially purified and the some properties were demonstrated. Optimal pH 6.0,optimal temperature 37℃ and the enzyme reaction was inhibited with some heavy metals and SH-inhibitors.

収録刊行物

  • ビタミン

    ビタミン 26 (3), 217-221, 1962

    公益社団法人 日本ビタミン学会

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