Effect of Dietary Composition on Vitamin B_6 Deficiency State. : (I) ON THE DIETARY PROTEIN LEVELS AND LIVER TRANSAMINASE ACTIVITIES IN RATS.

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  • OKADA Mitsuko
    Department of Nutrition, School of Medicine, Tokushima University
  • OCHI Atsuko
    Department of Nutrition, School of Medicine, Tokushima University

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Other Title
  • ビタミンB_6欠乏症に及ぼす食餌組成の影響 : (I) 食餌中のたん白量と肝酵素活性について
  • 食餌中のたん白量と肝酵素活性について
  • ショクジ チュウ ノ タンパクリョウ ト キモ コウソ カッセイ ニ ツイテ

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Description

Effect of vitamin B_6 was investigated on rats fed on diet containing different levels of protein. The growth of rats on 70% casein diet was retarded in a week after the vitamin B_6 depletion, while that of rats received 10% casein diet was normal during 4 weeks period regardless of diet with or without vitamin B_6. Liver transaminase activities (alanine, aspartate and ornithine transaminases) of rats were determined. Rats on B_6-depleted high protein diet were decreased in all liver transaminase activities measured and especially soluble alanine transaminase was most labile on the vitamin B_6 depletion. Soluble aspartate transaminase which is known to be induced by high protein administration was low in the livers of rats on B_6-depleted high protein diet rather than in that on low protein diet. Ornithine transaminase activity was found to be largely decreased in terms of holo-enzyme.

Journal

  • VITAMINS

    VITAMINS 43 (5), 237-240, 1971

    THE VITAMIN SOCIETY OF JAPAN

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