Fundamental Experiments on Respiratory ^<14>CO_2 after Administration of ^<14>C-Thiamine (2-C-Thiazole Labeled) to Rats

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Other Title
  • ^<14>C-Thiamine(2-C-Thiazole標識)投与シロネズミにおける呼気中^<14>CO_2排泄に関する基礎的研究
  • 14C Thiamine 2 C Thiazole ヒョウシキ トウヨ シロネ

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Description

In various conditions, respiratory ^<14>CO_2 was determined after administration of ^<14>C-thiamine to rats and following results were obtained. 1. ^<14>CO_2 was excreted in the expiration rapidly within 6 hours after ^<14>C-thiamine administration and then slowly excreted until 24 hours. However, after 24 hours expired ^<14>CO_2 was not detected. 2. Linear relationship was observed between expired ^<14>CO_2 and amounts of injected ^<14>C-thiamine up to 100μg of administered ^<14>C-thiamine per 100g of body weight of rats. When administered ^<14>C-thiamine exceed 100μg per 100g of body weight, ratio of ^<14>CO_2 to administered ^<14>C-thiamine was decreased. 3. Amounts of expired ^<14>CO_2 per body weight was constant when fixed amounts of ^<14>C-thiamine per body weight was administered to rats.

Journal

  • VITAMINS

    VITAMINS 52 (1), 31-34, 1978

    THE VITAMIN SOCIETY OF JAPAN

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