The Catabolism Nicotinamide in Riboflavin-Deficient Rats
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- SHIBATA Katsumi
- Department of Food Science and Nutrition,Teikoku Women's University
Bibliographic Information
- Other Title
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- リボフラビン欠乏ラットのニコチンアミド異化代謝
- リボフラビン ケツボウ ラット ノ ニコチンアミド イカ タイシャ
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Abstract
The catabolism of nicotinamide in riboflavin-deficient rats was compared with that in control rats. In riboflavin-deficient rats, no activities of N^1-methyl-2-pyridone-5-carboxamide (2-Pyr)-forming N^1-methylnicotinamide (MNA) oxidase and N^1-metyl-4-pyridone-3-carboxamide (4-Pyr)-forming MNA oxidase were not detected in vitro, however, the nicotinamide methyltransferase activity was not changed compared with the control rats. As a result, the excretion of MNA was higher in riboflavin-deficient rats than in control rats and the excretion of 2-Pyr and 4-Pyr was lower in riboflavin-deficient rats than in the control rats. Therefore, the resulting excretion ratio of (2-Pyr +4-Pyr )/MNA was greatly lower in the riboflavin-deficient rats than in the control rats.
Journal
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- VITAMINS
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VITAMINS 64 (10), 589-595, 1990
THE VITAMIN SOCIETY OF JAPAN
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Keywords
Details 詳細情報について
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- CRID
- 1390001205832781824
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- NII Article ID
- 110002848412
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- NII Book ID
- AN00207833
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- ISSN
- 2424080X
- 0006386X
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- NDL BIB ID
- 3696648
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed