Levels of NAD, NADP and Their Related Compounds in Human Blood

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  • SHIBATA Katsumi
    Department of Food Science and Nutrition, Teikoku Women's University
  • MATSUO Hiroko
    Department of Food Science and Nutrition, Teikoku Women's University

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Other Title
  • ヒト血液中のNAD,NADP及びその関連化合物含量
  • ヒト ケツエキチュウ ノ NAD NADP オヨビ ソノ カンレン カゴウブツ

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Levels of total NiA-NH_2, NAD (NAD^++NADH), NADP (NADP^++NADPH), N^1-methylnicotinamide (MNA), N^1-methyl-2-pyridone-5-carboxamide (2-Pyr) and N^1-methyl-4-pyridone-3-carboxamide (4-Pyr) in whole blood were measured using women students. As the results, total NiA-NH_2 level was around 60nmol/ml whole blood, NAD level around 30nmol/ml, NADP level 10nmol/ml. When the value of [total NiA-NH_2-(NAD+NADP)] is presumed to be free NiA-NH_2, its level would be around 20nmol/ml whole blood. The levels of catabolic metabolite from NiA-NH_2 such as MNA, 2-Pyr and 4-Pyr in whole blood were trace or below the limit of detection.

Journal

  • VITAMINS

    VITAMINS 63 (11), 569-572, 1989

    THE VITAMIN SOCIETY OF JAPAN

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