1P2-W07 蠕動運動する微小チューブ状筋組織バイオアクチュエータの光遺伝学による制御

DOI Web Site

書誌事項

タイトル別名
  • 1P2-W07 Living Peristaltic Micro Conveyor Tube of Optogenetically Controllable Bioactuator

説明

This paper reports a muscle-powered miniaturized cylindrical conveyor which has peristaltic movement and bending motion. In our study, we used two types of Drosophila melanogaster (DM, fruit fly) larvae that express GCaMP calcium indicator or channelrhodopsin-2 (ChR2) in the cell membrane of skeletal muscles. We observed calcium ions wave on living larvae due to muscle contraction and determined the optimum light condition. Then we controlled speed and width of the peristaltic waves of DM larvae with blue light by using optogenetic method. By changing speed of the propagating light wave while fixing the width of stimulation area, we tested contractile displacement. We succeeded in transporting micro beads arbitrarily by combining a variety of local stimulations.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ