9 Structures of Allosamidins, Novel Insect Chitinase Inhibitors, Produced by Microorganisms

Bibliographic Information

Other Title
  • 9 微生物の生産する昆虫のキチナーゼ阻害物質allosamidin類の構造

Description

Allosamidin(1), a novel insect chitinase inhibitor, was isolated from the mycelium of Streptomyces sp. Allosamidin showed strong inhibitory activity against the chitinases of the silkworm, Bombyx mori, in vitro, and also prevented its larval ecdysis in vivo. The structure of allosamidin was elucidated as 1 by acid hydrolysis experiments and analysis of 2D-NMR spectra. 1 is a basic pseudotrisaccharide consisting of N-acetyl-D-allosamine and a novel aminocyclitol derivative(3), termed allosamizoline. Methylallosamidin(2) was isolated from the mycelium of the unidentified actinomycetes and characterized as 2 by spectral comparison with 1.

Journal

Details 詳細情報について

  • CRID
    1390001206073243392
  • NII Article ID
    110006678539
  • DOI
    10.24496/tennenyuki.28.0_65
  • ISSN
    24331856
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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