Analysis of Newly Distributed Designer Drugs Detected in the Products Purchased in Fiscal Year 2008
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- UCHIYAMA Nahoko
- National Institute of Health Sciences (NIHS)
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- MIYAZAWA Norimasa
- Saitama Institute of Public Health
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- KAWAMURA Maiko
- National Institute of Health Sciences (NIHS)
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- KIKURA-HANAJIRI Ruri
- National Institute of Health Sciences (NIHS)
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- GODA Yukihiro
- National Institute of Health Sciences (NIHS)
Bibliographic Information
- Other Title
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- 2008年度買い上げ違法ドラッグ製品から検出された新規流通デザイナードラッグの同定
- 2008ネンド カイアゲ イホウ ドラッグ セイヒン カラ ケンシュツ サレタ シンキ リュウツウ デザイナードラッグ ノ ドウテイ
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Abstract
Thirty-two psychotropic substances were listed as designated substances (Shitei-Yakubutsu, 31 compounds and 1 plant) in Japan by the Pharmaceutical Affairs Law in April 2007 for preventing the abuse of these substances. Subsequently, other psychoactive compounds were also added to this category, 40 substances (classified as 12 tryptamines, 17 phenethylamines, 3 piperazines, 6 alkyl nitrites, 1 diterpene and 1 plant) are controlled as designated substances as of July 2009. However, new designer drugs are still distributed in illegal drug market according to the results of our annual survey. This study presents the analysis of four newly distributed designer drugs detected from two products, which were purchased from October 2008 to February 2009 in Japan. As the results of NMR, GC-MS and LC-MS analyses, three phenethylamine derivertives, 1-(2-fluorophenyl)-N-methylpropan-2-amine (N-Me-2-FMP), 1-(2,5-dimethoxy-4-isopropylsulfanylphenyl)propan-2-amine (ALEPH-4) and 1-(2,5-dimethoxy-4-nitrophenyl)propan-2-amine (DON) and a tryptamine derivative, N-ethyl-5-methoxy-N-propyltryptamine (5-MeO-EPT), were detected. N-Me-2-FMP and 5-MeO-EPT were newly identified in this study. Additionally, ALEPH-4 and DON were found as novel illegal drugs distributed in Japan.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 130 (2), 263-270, 2010-02-01
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001206126769792
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- NII Article ID
- 130000171296
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- NII Book ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 10545636
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed