New Progressing Crystallization Technology of Membrane Protein and Introduction of Pharamaceutical Innovation Value Chain
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- INOUE Tsuyoshi
- Graduate School of Engineering Osaka University NPO BioGrid Center Kansai
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- ADACHI Hiroaki
- Graduate School of Engineering Osaka University
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- MURAKAMI Satoshi
- Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University
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- TAKANO Kazufumi
- Graduate School of Engineering Osaka University
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- MATSUMURA Hiroyoshi
- Graduate School of Engineering Osaka University
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- MORI Yusuke
- Graduate School of Engineering Osaka University
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- FUKUNISHI Yoshifumi
- National Institute of Advanced Industrial Science and Technology (AIST)
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- NAKAMURA Haruki
- NPO BioGrid Center Kansai Research Center of Structural and Functional Proteomics, Institute for Protein Research, Osaka University
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- KINOSHITA Takayoshi
- Department of Applied Biochemistry, Graduate School of Agriculture and Life Sciences, Osaka Prefecture University
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- NAKANISHI Isao
- Graduate School of Pharmaceutical Sciences, Kyoto University
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- OKUNO Yasushi
- Graduate School of Pharmaceutical Sciences, Kyoto University
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- MINAKATA Satoshi
- Graduate School of Engineering Osaka University
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- SHIMOJO Shinji
- NPO BioGrid Center Kansai Cybermedia Center, Osaka University
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- SAKATA Tsuneaki
- NPO BioGrid Center Kansai Cybermedia Center, Osaka University
Bibliographic Information
- Other Title
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- 膜タンパク質の結晶化技術の新展開及び創薬バリューチェインの紹介
- マク タンパクシツ ノ ケッショウカ ギジュツ ノ シンテンカイ オヨビ ソウヤク バリュー チェイン ノ ショウカイ
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Description
We have recently established a Pharamaceutical Innovation Value Chain in collaboration with the SOSHO project (http://www.so-sho.jp) and BioGrid Project (http://www.biogrid.jp/) to accelerate new drug development. The SOSHO project provides novel crystallization technology with laser-irradiation and stirring growth methods, and the BioGrid Project is developing the software necessary for the in silico screening of promising drugs and the simulation of biological responses to proteins. In this paper, we report the recent research work on the crystallization of membrane proteins and the development of a method for in silico drug discovery.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 128 (4), 497-505, 2008-04-01
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390001206127626368
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- NII Article ID
- 110006656188
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- NII Book ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 9463144
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed