書誌事項
- タイトル別名
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- Analysis of Benoxaprofen Glucuronide in Human Plasma and Urine by Gas Chromatography
- ガス クロマトグラフィー ニヨル ヒト ケッチュウ オヨビ ニョウチュウ ノ
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The main metabolite of benoxaprofen (BXP), an acidic anti-inflammatory analgesic, was isolated from human urine and identified as a glucuronide of BXP (BXP-G). BXP-G could be also detected in human blood though the amount was very slight. An improvement was attempted to the hydrolysis process in the assay method for BXP-G described by Chatfield, et al. BXP-G in urine or plasma could be rapidly and completely hydrolyzed to BXP in potassium hydroxide without any additional degradation. Thus, the present method was more accurate and less time-consuming for the assay of BXP-G than the Chatfield's method.
収録刊行物
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- 薬学雑誌
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薬学雑誌 103 (1), 54-61, 1983
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001206128081280
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- NII論文ID
- 110003661064
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 2622705
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- データソース種別
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- JaLC
- NDL
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