A Randomized Controlled Study on the Effectiveness of Community Pharmacists' Advice for the Smoking Cessation by Nicorette —Evaluation at Three Months after Starting the Cessation—

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  • MOCHIZUKI Mayumi
    Division for Evaluation and Analysis of Drug Information, Center for Clinical Pharmacy and Clinical Sciences, Kitasato University, School of Pharmacy
  • HATSUGAYA Masaki
    Division for Evaluation and Analysis of Drug Information, Center for Clinical Pharmacy and Clinical Sciences, Kitasato University, School of Pharmacy
  • ROKUJOH Emiko
    Division for Evaluation and Analysis of Drug Information, Center for Clinical Pharmacy and Clinical Sciences, Kitasato University, School of Pharmacy
  • ARITA Etsuko
    Pharmaceutical Education Research Center, Kitasato University, School of Pharmacy
  • HASHIGUCHI Masayuki
    Division for Evaluation and Analysis of Drug Information, Center for Clinical Pharmacy and Clinical Sciences, Kitasato University, School of Pharmacy
  • SHIMIZU Naokata
    Controller Committee
  • TAKEUCHI Masahiro
    Division of Biostatistics, Center for Clinical Pharmacy and Clinical Sciences, Kitasato University Graduate School
  • YAMAMOTO Nobuo
    Japan Pharmaceutical Association
  • AKIBA Yasutsugu
    Japan Pharmaceutical Association

Bibliographic Information

Other Title
  • ニコレット<sup>®</sup>による禁煙達成に及ぼす保険薬局薬剤師の禁煙指導の有効性に関するランダム化群間比較調査研究 —禁煙開始3ヵ月後での評価—
  • ニコレットによる禁煙達成に及ぼす保険薬局薬剤師の禁煙指導の有効性に関するランダム化群間比較調査研究--禁煙開始3ヵ月後での評価
  • ニコレット ニ ヨル キンエン タッセイ ニ オヨボス ホケン ヤッキョク ヤクザイシ ノ キンエン シドウ ノ ユウコウセイ ニ カンスル ランダムカグン カン ヒカク チョウサ ケンキュウ キンエン カイシ 3カゲツ ゴ デ ノ ヒョウカ

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Abstract

  We conducted a randomized, controlled study to evaluate whether pharmacists' advice on smoking cessation would result in a higher smoking cessation rate using Nicorette (nicotine gum preparation). Fourteen pharmacies in Tokyo, Kanagawa, and Nagano participated. Smokers who visited pharmacies to buy Nicorette from March 1, 2002, through August 31, 2002, were recruited and randomly assigned to two groups. For the intervention group (A), pharmacists provided both regular instructions on Nicorette use and smoking cessation advice at the first sale and then gave follow-up advice just before starting a cessation and 1, 3, and 8 weeks and 3 months thereafter. For the control group (B), pharmacists provided regular instructions alone. The primary outcome measure was the self-reported smoking cessation rate and the secondary outcome measure was the relationship between the smoker's egogram and effectiveness of intervention. Twenty-eight smokers were enrolled and randomized into group A (n=11) or group B (n=17). The absolute abstinence rate in groups A and B at 3 months was 45.5% and 31.2%, respectively. The odds ratio was 1.83, which was not statistically significant. There was no difference in egogram score between absolute abstinence subjects and nonabstinence subjects in group A. The egogram scores in Adapted Child of absolute abstinence subjects in group B were significantly higher than in nonabstinence subjects. In conclusion, instructions and advice given by pharmacists may improve the smoking cessation rate in smokers receiving nicotine replacement therapy.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 124 (12), 989-995, 2004-12-01

    The Pharmaceutical Society of Japan

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